Micronutrients and Diabetes

Patented technology to help to optimize cellular sugar metabolism Natural health research – the basis of preventive health.

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Patented technology to help to normalize high blood sugar levels – naturally

More than 60 million people in Europe suffer from diabetes, and hundreds of thousands die each year from complications of this disease. Diabetic disorders have a genetic background and are divided into two types: juvenile diabetes (Type 1), and adult-onset diabetes (Type 2). Juvenile diabetes requires regular insulin injections from a young age. The majority of diabetic patients, however, develop this disease later in life. Until recently, the causes that trigger the sudden onset of the disease have been largely unknown, and treatment has consisted of lowering blood sugar levels with various drugs. However, diabetic cardiovascular complications occur even in those patients with controlled blood sugar levels. Thus, lowering blood sugar levels is a necessary but incomplete measure to address diabetic disorders.

New research shows that the primary cause of adult diabetes is a long-term deficiency of dietary vitamins and other essential nutrients in the cells of our body. This affects particularly the pancreas, the organ that produces insulin, and the blood vessel walls. Optimum intake of micronutrients can help to prevent the onset of adult diabetes and its complications.

Groundbreaking natural health research

Scientists at the Dr. Rath Research Institute have developed a combination of micronutrients that has been proven to affect decisive cellular mechanisms involved in diabetes.

  • Micronutrients increase glucose uptake by cells

One of the important ways to normalize elevated blood glucose levels is to optimize uptake of glucose by the cells of our body. The adjacent graph (A) shows that a combination of three micronutrient compositions (core, mineral and D3/K2), taken together, could enhance cellular glucose uptake more than fivefold compared to a control. Better cellular glucose uptake means less glucose in blood.

  • Micronutrients increase insulin secretion by pancreatic cells

Insufficient insulin production by the hormonal cells of the pancreas is a primary cause of diabetes. The results on the adjacent graph (B) show that specific micronutrient combinations can increase the secretion of insulin by pancreas cells in a natural way. At the highest micronutrient concentration tested in this study, the insulin secretion was twice as high as in controls. More insulin means more cellular glucose uptake and, hence, a lowering of high blood sugar.

  • Micronutrients help to protect nerve cells from diabetic damage

One of the long-term complications of diabetes is the deposition of dangerous byproducts generated by high glucose. These so-called Advanced Glycation End Products (AGEs*) include certain proteins, lipids and other compounds. By becoming encrusted with sugar molecules, these AGEs can have a toxic effect on all cells, and in particular on the cells of the nervous system. Further results show that a triple combination of micronutrients can protect up to 80% of nerve (glial) cells from the deadly damages caused by AGEs. The more cells surviving high glucose damage, the better the nervous system is protected in diabetes.

Vitamin C
Vitamin B1
Vitamin B2
Vitamin B3
Vitamin B5
Vitamin B6
Vitamin B12
Vitamin E
Cinnamon Extract
Green Tea Extract
Alpha-Lipoic Acid
Grape Seed Extract

Micronutrient combinations help to normalize high blood sugar levels

The following experiments were part of the scientific proof that led to the Patent Office approval of this natural technology to help fight diabetes.

Figure A shows that different micronutrient combinations (blue) can greatly increase the uptake of sugar by body cells, and thereby help to lower elevated blood sugar levels. Taken together, these micronutrient combinations can increase the sugar uptake more than five-fold compared to controls.

Figure B documents another breakthrough experiment from this patent. Micronutrient combinations can stimulate the production/secretion of insulin — the decisive sugar-level-regulating hormone – in human pancreas cells. Thus, optimum micronutrient supplementation contributes to optimum availability of insulin in healthy people and to insulin-sparing in diabetic patients.

A. Micronutrient combinations increase cellular sugar uptake as a precondition for normalizing high blood sugar

B. Micronutrient combinations increase insulin secretion of human pancreas cells

Allowed patent claims:

  • A micronutrient composition used for treating diabetes … by increasing cellular glucose uptake and increasing insulin production.
  • A micronutrient composition that protects a glial cell against damage by AGEs.

Nobel Prize‐winner‐supported research paves the way to preventive health care

The Dr. Rath Research Institute is a world leader in science-based natural health. Three decades ago, Dr. Matthias Rath – together with two-time Nobel Laureate Dr. Linus Pauling (†1994) – was already publishing groundbreaking discoveries on the importance of vitamins in fighting cardiovascular diseases. Over the ensuing decades, the Institute’s research team, under the leadership of Dr. Aleksandra Niedzwiecki, has extended this lifesaving research to comprise natural prevention of cancer, diabetes, viral and bacterial infections and many other diseases. The approval of this preventive health research by patent offices around the world provides the scientific basis for effective preventive health strategies globally. Patients, therapists, governments and, above all, millions of people now have effective, safe, natural health approaches available to help to prevent widespread diseases.

The Dr. Rath organization operates under a non-profit roof and all profits are used to promote further independent research and education in natural health. This page provides health research established in connection with natural disease prevention. For patients, we recommend to see a therapist or trained consultant to determine your individual health needs.

‘Science‐based natural health is the basis of modern, preventive health care. The time to build it is now!’

Dr. Matthias Rath

What this patent means

This specific health technology is

  • recognized by a government agency,
  • novel and has not existed before,
  • unique and not available anywhere else,
  • protected and cannot be imitated.

What is the difference from a pharmaceutical drug patent?

investment business
Natural health
Target markets Disease management Disease prevention
Purpose of patents Legal tools to secure
return on investment
for your health
Cementing continuation
of diseases as
global markets
Disease prevention
and potential
Consequences for
national economies
health care costs
Less diseases = lower
health care costs

Supporting Studies

Type 1

Combination of B vitamins as a safe and effective therapy for early-stage diabetic nephropathy in children with type 1

Effect of vitamin D supplementation in children with type 1 diabetes

Effect of vitamin D on glucose levels in children and adolescents with diabetes type 1

Chromium, zinc and magnesium status in type 1 diabetes

Immunomodulatory effect of vitamin D and its potential role in the prevention and treatment of type 1 diabetes mellitus

The role of vitamin D supplementation in patients with diabetes type 1

Type 2

Effect of oral vitamin D supplementation on glucose regulation in patients with type 2 diabetes

Association of dietary vitamin D and E intake in type 2 diabetes patients

The effects of a combined magnesium and zinc supplementation in patients with type 2 diabetes and coronary heart disease

Vitamin C supplementation improves regulation of glucose levels and blood pressure in patients with type 2 diabetes

Vitamin D supplementation in adults with (pre)diabetes type 2

Effect of vitamin D supplementation on glucose parameters and progression of prediabetes to diabetes

The beneficial role of a micronutrient supplementation on neuropathy in type 2 diabetic patients

Effects of zinc and other micronutrients on glucose and lipid regulation in adult diabetes

Effect of folic acid supplementation on various metabolic factors in overweight and obese men with type 2 diabetes

Effect of magnesium supplementation on glucose metabolism in people with or at risk of diabetes

Gestational Diabetes

Effect of vitamin D supplementation on pregnant women with gestational diabetes mellitus

Zinc supplementation and its effects on metabolism in gestational diabetes

Effects of selenium supplementation on glucose regulation, inflammation, and oxidative stress in gestational diabetes

The effects of magnesium and vitamin E co-supplementation on parameters of glucose regulation and lipid metabolism in patients with gestational diabetes

Role of vitamin D and calcium supplementation on metabolism and oxidative stress in gestational diabetes mellitus

Magnesium, zinc, calcium, and vitamin D improve glucose regulation and risk factors of heart diseases in gestational diabetes

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